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Sofosvel- first generic Hepatitis C cure of Epclusa

Reasonable price’s Sofosvel/ Generic Epclusa cure rate is very good for all genotype. Virus undetected quickly after starting treatment!

Sofosvel (400mg Sofosbuvir + 100mg Velpatasvir)

Sofosvel (Sofosbuvir / Velpatasvir) / Generic Epclusa Description:

US based Gilead Pharmaceuticals company invented Epclusa (Sofosbuvir / Velpatasvir) preparation to treat all genotype of Hepatitis C disease. Epclusa cure rate is higher than all other previous Hepatitis C Drugs. As a result Epclusa is a great medication for Hepatitis C Disease. This tablet is recently approved by US FDA and European Commission for Giliead’s company named “Epclusa”. Which price around $75000 USD for only 84 tablets of 12 weeks course! Not Joking, It’s the price of Gilied’s Epclusa! And that’s not affordable for Hepatitis C patients globally.

From that sense, Beacon Pharmaceuticals Ltd launched their 3rd product “Sofosvel” as a first generic global product to make Hepatitis C treatment affordable globally. Previous products were Darvoni (Sofosbuvir + Daclatasvir) for all genotypes Hepatitis C patients and Tagrix (osimertinib) for lung cancer.

Sofosvel is the world’s first generic oral medicine of Sofosbuvir 400mg & Velpatasvir 100mg. Manufactured by Beacon Pharmaceuticals Limited, Bangladesh. Reasonable price’s Sofosvel is used for pan-genotypic Chronic Hepatitis C treatment. It means It will be worked for all genotype 1, 2, 3, 4, 5 & 6.

Sofosvel (400mg Sofosbuvir + 100mg Velpatasvir)

Difference of Branded Epclusa and generic Epclusa (Sofosvel) price:

Branded Epclusa Price almost $75000 USD for standard 12 weeks treatment. Where Generic Epclusa (Sofosvel) price $840 USD.


The reason of unbelievable high price of life saving ‘Brand Name’ medicines is “We’re in Business of Shareholder Profit, Not Helping the Sick”- J. Michael Pearson, The current CEO of Valeant.

Difference between Branded Epclusa and reasonable price’s Sofosvel medicine:

Some patients think generic Epclusa (Sofosvel) is not same as Brand Eplcusa. They may be uncertain about using generic drugs initially. But they are in fact more likely to adhere to treatment when prescribed lower cost generics.

Brand name drugs also called ‘innovator drugs’. Originator develops an innovative medicine and holds a patent on it for 20-25 years. The price of medicine is usually very high to cover for research and development, marketing costs, and of course profit. Generic Drugs are copies of brand name drugs. Usually generic drugs produced after the original patent expires, but the case of generic Epclusa (Sofosvel) is different. According to LDC (Least Development Country) rules, Bangladeshi pharma companies can copy and manufacture any patent medicine under Directorate General of Drug Administration & Licensing Authority (Drugs) of Bangladesh. And also other hand, the manufacturer of Brand medicine Epclusa allowed some companies to create generic versions of Epclusa before the patent’s expiry, that’s why first generic Epclusa (Sofosvel) launched only after 2 months of launching originator’s Epclusa.

This is why the  generic Epclusa (Sofosvel) cost $840. This is a reasonable cost to treat all genotype of Hepatitis C disease. 

Generic and brand name drugs have identical active ingredients. generic drugs must meet  standards for bio equivalence. Bio equivalent drug formulations have the same bio availability that explore same rate and extent of absorption. New drug formulations must meet standards. If the generic drug is bio equivalent, it is assumed that it will produce the same therapeutic effect as the brand name drug. That’s why new clinical studies are not needed for generic drugs.

Generic Sofosvel must have the same (to a certain point) characteristics as the original Epclusa in order to get FDA approval as a generic. The company that created first copies of (sofosbuvir / velpatasvir) tablets had to show that these tablets are the same as the one from the originator’s.


Sofosvel is registered and licensed by regulatory authority of Bangladesh:


Sofosvel is the global first generic oral tablet for pan-genotypic Chronic Hepatitis C treatment. This combination (Sofosbuvir / Velpatasvir) drug has been approved by US FDA & European Commission for treatment of patients with all genotype Chronic Hepatitis C virus infection. Sofosvel is used without cirrhosis or with compensated cirrhosis, and patients with advanced cirrhosis (Decompensated).

Generic Sofosvel with or without Ribavirin for HIV/ HCV Coinfected patients clinical studied in Taiwan sponsored by National Taiwan University Hospital.  

Generic Velpatasvir plus Sofosbuvir with or without Ribavirin for the treatment of Hepatitis C virus in patients co-infected with Human Immunodeficiency Virus (HIV).

“Data are limited regarding the effectiveness and safety of generic velpatasvir plus sofosbuvir (VEL/SOF) with or without ribavirin (RBV) for the treatment of hepatitis C virus (HCV) in patients with human immunodeficiency virus (HIV) coinfection. We aim to compare the effectiveness and safety of VEL/SOF with and without RBV for 12 weeks in HIV/HCV-coinfected and HCV-monoinfected patients The antiviral responses and the adverse events (AEs) are compare between the two groups. The characteristics potentially related to sustained virologic response 12 weeks off therapy (SVR12) are analyzed.” –
Generic VEL/SOF With or Without RBV for HIV/HCV Coinfected Patients

Is it legal to import reasonable price’s Generic Epclusa/ Sofosvel globally?

According to WTO rules, Generic Epclusa (Sofosvel) is available to supply worldwide under ‘patient Support program’. Not only that, but also the treatment drugs of life threatening diseases such as hepatitis, cancer etc are globally available to supply under ‘patient support program’ for personal use.


Therapeutic indications:

Sofosvel is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5 or 6 infections.

• With or without cirrhosis or with compensated cirrhosis

• With decompensated cirrhosis for use in combination with Ribavirin

Sofosvel Pharmaceutical Form:

Product Name : Sofosvel

Generic Name : Sofosbuvir 400mg + Velpatasvir 100 mg

Formulation     : Solid dosage form (Tablet)

pack size        : 1×6’s Strip box or 1×28’s Pot

Certificate of Analysis (COA) of Generic Epclusa (Sofosvel):


COA of Sofosvel updated


Certificate of Analysis (COA) of Sofosvel



To order Sofosvel (Sofosbuvir 400 mg + Valpatasvir 100 mg), Please submit your details on the order page. Then we will arrange your shipment.